James Middleton Cox (March 31, 1870 – July 15, 1957) was an American businessman and politician who served as the 46th and 48th governor of Ohio, and a two-term U.S. Representative from Ohio. As the Democratic nominee for President of the United States at the 1920 presidential election, he lost in a landslide to fellow Ohioan Warren G. Harding. His running mate was future president Franklin D. Roosevelt. He founded the chain of newspapers that continues today as Cox Enterprises, a media conglomerate.

Born and raised in Ohio, Cox began his career as a newspaper copy reader before becoming an assistant to Congressman Paul J. Sorg. As owner of the Dayton Daily News, Cox introduced several innovations and crusaded against the local Republican Party boss. He served in the United States House of Representatives from 1909 to 1913 before being elected as Governor of Ohio. As governor, Cox introduced a series of progressive reforms and supported Woodrow Wilson's handling of World War I and its aftermath.

He was chosen as the Democratic nominee for president on the forty-fourth ballot of the 1920 Democratic National Convention. Running on a ticket with future President Franklin D. Roosevelt as his vice presidential running mate, Cox suffered the worst popular vote defeat (a 26.17% margin) since the unopposed re-election of James Monroe in 1820.

Cox retired from public office after the 1920 presidential election to focus on his media conglomerate, which expanded into several cities. By 1939, his media empire extended from Dayton to Miami. He remained active in politics, supporting Roosevelt's campaigns and attending the 1933 London Economic Conference.