Sixto María Durán Cárdenas (August 6, 1875 – January 13, 1947) was an Ecuadorian pianist, composer, and lawyer.

Durán Cárdenas was born in Quito on August 6, 1875. He earned a law degree from the Central University of Ecuador in 1889. While he was a renowned, award-winning music composer, he continued to practice law throughout his lifetime because in Ecuador musical careers were not well-paid.

In 1900 President Eloy Alfaro appointed him Intermediate Piano Professor of the newly reopened National Conservatory of Music. In 1911 President Emilio Estrada Carmona appointed him the director of the National Conservatory of Music. He took on this position again in 1923 (for 10 years) and again from 1941-1943.

In 1916 he was the director of the School of Arts and Crafts. In 1918 he suffered a serious accident at the school, where the fingers of his left hand were severed by a machine. While his career as a pianist was over, he continued as a composer throughout his life. His musical works number over 150.

Besides folk music, he liked to compose classical music and chamber music. He also wrote articles for several magazines and newspapers.

In 1946 he began suffering from nephritis, and he died at the age of 71 on January 13, 1947.